Cautions

Posted By: Lukasz Malwina In: Patients Information On: Comment: 0 Hit: 375

Medical marijuana and CBD, in particular, are a very safe, but patients taking other medications should check with their doctor about drug interactions. At sufficient dosages, CBD will temporarily deactivate cytochrome P450 enzymes, thereby altering how we metabolize a wide range of compounds. 

Medical marijuana and CBD, in particular, are a very safe, but patients taking other medications should check with their doctor about drug interactions. At sufficient dosages, CBD will temporarily deactivate cytochrome P450 enzymes, thereby altering how we metabolize a wide range of compounds. 

Cytochrome P450 enzymes metabolize more than 60 percent of pharmacueticals. CBD is a more potent inhibitor of cytochrome P450 than the grapefruit compound Bergapten, so ask your doctor if grapefruit interacts with your medication. If grapefruit does, then CBD probably does, too. Patients on medical marijuana should monitor changes in blood levels of prescription medications and, if need be, make adjustments as directed by their doctor.

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